Microalgal-derived biofuels are currently paving the way towards sustainable and green energy generation. The current study targets to bring in multiway novelties in this direction through generating substantial biomass and lipid yields in a single cultivation cycle, lower experimental time, less chemical utilization and enhanced biodiesel quality. It also ensures higher costeffectivity, mass applicability and promising annual outcomes. In the present work, a marine microalga Picochlorum soloecismus was subjected to an extensive range of macronutrient stresses to elevate its storage lipids. Amongst all the factors studied, 4 best parameters, i.e., concentrations of NaCl and nitrate, initial culture pH, and incubation period were optimized and a...